Neuroscience Portfolio

Explore the Mouse Biology Program’s neuroscience portfolio, featuring specialized resources and services to advance research in brain function, behavior, and neurological disorders.

Our Neuroscience Portfolio equips researchers with advanced tools and resources to study the complexities of the brain, nervous system disorders, and behavioral phenotypes. By leveraging diverse mouse models, phenotyping platforms, and cutting-edge experimental tools, we support neurodevelopment, neurodegeneration, and neuroinflammation discoveries. Our offerings include models for investigating genetic mutations, synaptic function, and disease progression in disorders such as Alzheimer’s, Parkinson’s, autism spectrum disorders, and more. With expert consultation and robust data support, the portfolio empowers researchers to uncover deeper insights into the molecular and cellular mechanisms underlying nervous system diseases with some of the following services:

Mouse Models for Neuroscience Research
Behavioral and Cognitive Testing
Neuropathology and Functional Imaging
Electrophysiology and Neural Activity Monitoring

Mouse Models for Neuroscience Research

We offer a comprehensive collection of mouse models designed for the study of neurological functions and diseases, including:

Genetically Engineered Mouse Models (GEMMs): For studying neurological mutations and disease mechanisms.
Neuroinflammation and Immune-Response Models: For assessing the impact of neuroimmune interactions in disorders like multiple sclerosis (MS) and traumatic brain injury (TBI).
Behavioral and Cognitive Research Models: Exploring memory, learning, and behavioral phenotypes.

Behavioral and Cognitive Testing

Our neuroscience services support in vivo studies with validated assays to assess:

Motor Function: Tests for balance, coordination, and muscle strength (e.g., rotarod test).
Memory and Learning: Cognitive function assays like Morris water maze and fear conditioning tests.
Sensory and Emotional Responses: Exploration of sensory processing, anxiety-related behaviors, and social interaction.

Neuropathology and Functional Imaging

We provide specialized services for comprehensive analysis of neurological function and pathology:

Histological Analysis: Examination of neuronal degeneration, axonal damage, and synaptic density.
Immunohistochemistry (IHC): To visualize protein expression and detect pathological markers.
Imaging Platforms: Advanced microscopy and MRI services to assess structural and functional changes in the brain.

Electrophysiology and Neural Activity Monitoring

For researchers investigating neural signaling, our platform supports:

Electrophysiology Studies: Measuring neuronal excitability and synaptic transmission.
In Vivo Neural Recording: Real-time monitoring of brain activity during behavioral assays.
Optogenetics and Calcium Imaging: Tools to study neural circuits and neuronal dynamics in live animals.

Why Choose Our Neuroscience Services?

Diverse Model Access: Access to a broad range of mouse models for neurodevelopmental and neurodegenerative research.
Comprehensive Testing and Analysis: Full-service phenotyping and neuropathology support for complex studies.
Data Integration: Robust data outputs, including behavioral performance, molecular profiling, and imaging reports.

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Advance your neuroscience research with our models and services that support brain and nervous system investigations.

Ask How the Mouse Biology Program Enhances Neuroscience Research

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