The Mouse Biology Program supports disease research by providing advanced resources, specialized services, and expert guidance to develop and utilize mouse models for understanding, preventing, and treating human diseases.
The Mouse Biology Program (MBP) offers a variety of resources and services that support research across multiple disease areas. MBP enables researchers to explore disease mechanisms, test therapies, and develop targeted treatments by providing tools for creating, studying, and managing mouse models. Here’s how our core services align with specific disease types:
Genetic Diseases
Metabolic Disorders
Neurological Disorders
Cancer Research
Autoimmune and Inflammatory Diseases
Cardiovascular Diseases
Genetic Diseases
The Mouse Biology Program provides mouse models critical for exploring the genetic basis of human diseases. These models allow researchers to investigate gene function and mutation impacts, enabling the development of targeted therapies and gene-editing approaches.
Supports discovery of genetic mutations that cause diseases.
Enables precision medicine by modeling human gene variants.
Metabolic Disorders
Our models support studies on metabolic disorders like diabetes and obesity. By enabling precise evaluation of metabolic pathways and interventions, MBP accelerates research on treatments to improve health outcomes.
Facilitates understanding of metabolic dysfunctions and energy balance.
Drives the development of therapies for obesity and diabetes.
Neurological Disorders
MBP offers models for studying neurological conditions such as Alzheimer’s and Parkinson’s disease. These tools help researchers uncover mechanisms underlying brain function and identify potential therapeutic strategies.
Advances understanding of neurodegenerative disease progression.
Enables preclinical testing of drugs for brain disorders.
Cancer Research
Mouse models play a pivotal role in cancer research, enabling studies on tumor progression, metastasis, and the efficacy of novel therapies. MBP provides resources that advance understanding and treatment of various cancers.
Supports investigation of genetic and environmental causes of cancer.
Facilitates testing and optimization of cancer therapies.
Autoimmune and Inflammatory Diseases
Our mouse models facilitate research into autoimmune and inflammatory conditions such as arthritis and lupus. These models help evaluate immune system function and test interventions to modulate inflammation.
Enables discovery of triggers and pathways in autoimmune diseases.
Tests treatments to control chronic inflammation effectively.
Cardiovascular Diseases
MBP supports research on cardiovascular diseases by providing models to study heart disease, hypertension, and atherosclerosis. These resources enable advances in prevention and treatment strategies for improving heart health.
Promotes understanding of mechanisms behind heart disease.
Advances research on innovative treatments for vascular disorders.
Advancing Disease Research with MBP Resources
The Mouse Biology Program (MBP) advances biomedical research by providing essential mouse models for studying diseases like cancer, neurological and metabolic disorders, and more. These resources drive discoveries, bridging basic research and clinical breakthroughs to improve global health.