Gnotobiotic Mouse Resource Center (GMRC)

Advancing Microbiota Research with Germ-Free Mice, Study Design Expertise, and Specialized Procedures with a partnership with the Mouse Biology Program.


The Gnotobiotic Mouse Resource Center (GMRC) offers comprehensive services supporting microbiota studies, specializing in germ-free conditions and managing gnotobiotic experiments. Services include:

  • Breeding and Colony Management: Setting up and maintaining breeding units with live data updates through the MOSAIC colony management database.
  • Tailored Housing Options: Mice are housed in flexible isolators or individually ventilated cages, meeting specific research requirements while ensuring a controlled, sterile environment.
  • Precise Genotyping and Identification: Ear notching and tail cutting are performed for genotyping, with tissue samples available for in-house testing or customer pickup.
  • Sterility Assurance: Frequent microbiological testing confirms isolator sterility, maintaining a pathogen-free environment for reliable results.
  • Specialized Procedures: Services include colonization of defined flora via gavage, body weight monitoring, and fecal and urine collection for detailed analysis.

By combining expertise in gnotobiotic studies with state-of-the-art facility protocols, the GMRC ensures accuracy and reproducibility, supporting your microbiome research from start to finish.