Animal Health Reports for the Mouse Biology Program's Barrier-Maintained Mouse Facilities
The Mouse Biology Program bioinformatics team has direct experience with mouse model research. The group designs and maintains systems for high throughput genotyping and phenotyping, including data collection, hosting, visualization, and analysis, dynamic web presentation, and publication quality reporting.
Here at the Mouse Biology Program (MBP), we have extensive experience with mouse breeding and colony management. Our trained professional staff can assist you with devising and implementing a breeding plan to generate the cohort or mouse model your research requires.
At the MBP, our cryopreservation and recovery services program provides you with the peace of mind and assurance that your research investment is protected. Our new advances in reproductive technologies allow us to cryopreserve and recover your mouse strains rapidly, reliably, and most important, cost-effectively.
The MBP offers a variety of services for mouse genotyping, customized to meet the needs of our clients.
A recent study highlights the importance of confirming gene disruption in knockout mice that use the "knockout-first" allele design. This approach, developed by the International Knockout Mouse Consortium, incorporates the En2 splice acceptor sequence and the lacZ reporter gene to facilitate gene function studies. While intended to disrupt gene function by interfering with normal splicing, the En2 sequence can sometimes be included in the host gene's mRNA. This inclusion may…Read more
A groundbreaking study at the University of Texas at Austin, highlighted by NIH Director Dr. Monica M. Bertagnolli, has brought…Read more
The year (2022-2023) marks 24 years since the UC Davis Mouse Biology Program (MBP) began serving the mouse modeling needs…Read more
Mouse Biology Program is in the process of an across the board rate review, affecting MBP, MMRRC at UC Davis,…Read more
Imagine the genome as a city with different neighborhoods, each having its function. Topologically associating domain (TAD) boundaries are like…Read more
