Animal Health Reports for the Mouse Biology Program's Barrier-Maintained Mouse Facilities
The Mouse Biology Program bioinformatics team has direct experience with mouse model research. The group designs and maintains systems for high throughput genotyping and phenotyping, including data collection, hosting, visualization, and analysis, dynamic web presentation, and publication quality reporting.
Here at the Mouse Biology Program (MBP), we have extensive experience with mouse breeding and colony management. Our trained professional staff can assist you with devising and implementing a breeding plan to generate the cohort or mouse model your research requires.
At the MBP, our cryopreservation and recovery services program provides you with the peace of mind and assurance that your research investment is protected. Our new advances in reproductive technologies allow us to cryopreserve and recover your mouse strains rapidly, reliably, and most important, cost-effectively.
The MBP offers a variety of services for mouse genotyping, customized to meet the needs of our clients.
Imagine the genome as a city with different neighborhoods, each having its function. Topologically associating domain (TAD) boundaries are like the fences that separate these neighborhoods, maintaining distinct regulatory territories. Disruption of these boundaries may interfere with regular gene expression and cause diseases, but the full impact remains unclear. Researchers utilized CRISPR genome editing in mice to investigate the consequences of deleting eight TAD boundaries. All deletions led to noticeable…Read more
Mutant mouse genetic modifications have revolutionized biomedical research, enabling scientists to study specific gene mutations and their effects on biological…Read more
By Claudia Coons The UC Davis Health Department of Surgery has received $3.75 million to launch a high-profile center where researchers…Read more
Launching the Next Decade of Service This past year (2020-2021) marks 22 years since the UC Davis Mouse Biology Program…Read more
By Andy Fell on August 3, 2020, in Human & Animal Health The National Institutes of Health has awarded a grant…Read more