Are You Interested in a Particular Gene
The IMPC is creating knockout mouse lines for every single protein coding gene in the mouse genome, and characterising them through standardised, quality-controlled phenotyping tests.
See the phenotypes for thousands of gene knockouts. Free database includes raw data, statistics, images, disease associations and interactive embryo viewer at http://www.mousephenotype.org
Now Available CRISPR/Cas9 for RATS!
NIH Renews Knockout Mouse Program (KOMP)
The Mouse Biology Program (MBP), has been awarded over $29 million from the National Institutes of Health under the next five-year phase of the Knockout Mouse Project, or KOMP. The MBP at UC Davis is the lead organization in a consortium involving research partners at The Centre for Phenogenomics in Toronto, Canada; the Children’s Hospital Oakland Research Institute, or CHORI; and Charles River Laboratories in Wilmington, Massachusetts.
The goal of this phase of the Knockout Mouse Project is to produce and phenotype knockout mouse models for up to 1,000 genes in an effort to better understand the genetic basis for diseases in humans and animals, said principal investigator Kent Lloyd, professor in the Department of Surgery in the UC Davis School of Medicine, and director of the UC Davis Mouse Biology Program