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Quality Control Services

The Mouse Biology Program is proud to offer an extensive tissue quality control service designed to accommodate researchers working with tissue samples from various sources. Our team of experienced professionals and state-of-the-art facilities are equipped to handle any tissue sample, ensuring your research’s highest quality and accuracy. We offer a comprehensive suite of Quality Control Services to ensure the accuracy and reliability of your mouse models. Our quality control services include:

  • Genetic background diversity: We assess the genetic background of your mouse lines to ensure uniformity and minimize confounding variables.
  • Allelic copy number (qPCR): We determine the copy number of your target allele using quantitative PCR, providing precise information about gene dosage.
  • Gene expression: We analyze gene expression levels to confirm the functionality and stability of your engineered alleles.
  • Allele sequence (bidirectional analysis): We perform bidirectional Sanger sequencing to verify your engineered alleles’ correct introduction and integrity.
    Genomic insertion site: We identify the precise genomic location of your transgene or targeted mutation to ensure the desired modification has been achieved.
  • RNA transcript sequence: We sequence RNA transcripts to verify your engineered alleles’ correct splicing, expression, and functionality at the transcript level.
    mRNA sequence: We sequence mRNA to confirm the accuracy of your target gene’s expression and validate the integrity of your mouse models.
  • Customized Solutions: We understand that each research project is unique, and our team is committed to providing customized solutions tailored to your needs. Simply let us know your requirements, and we will work with you to develop a quality control plan that meets your objectives.

With the Mouse Biology Program’s Comprehensive Quality Control Service, you can trust that your samples will be meticulously handled and analyzed, providing you with the confidence and reliability your research deserves. Contact us today to discuss your project and learn how we can support your research endeavors.

Genetic mistakes happen…we won’t let them go undetected.