Services & Products

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Bioinformatics and Analytics

The Mouse Biology Program bioinformatics team has direct experience with mouse model research. The group designs and maintains systems for high throughput genotyping and phenotyping, including data collection, hosting, visualization, and analysis, dynamic web presentation, and publication quality reporting.


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Breeding

Here at the Mouse Biology Program (MBP), we have extensive experience with mouse breeding and colony management. Our trained professional staff can assist you with devising and implementing a breeding plan to generate the cohort or mouse model your research requires.


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Cryopreservation

At the MBP, our cryopreservation and recovery services program provides you with the peace of mind and assurance that your research investment is protected. Our new advances in reproductive technologies allow us to cryopreserve and recover your mouse strains rapidly, reliably, and most important, cost-effectively.


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Genetics

The MBP offers a variety of services for mouse genotyping, customized to meet the needs of our clients.


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Import/Export

At the MBP, we have extensive experience with live mouse imports to the UC Davis campus, both from domestic and international facilities and also have extensive experience with exporting live mice and mouse samples (tissues, germplasm, ES cells, etc) worldwide.


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Molecular Genetics and Engineering

The MBP utilizes a variety of different techniques including BAC recombineering, Yeast Recombineering, Gibson Assembly Cloning, and traditional ligation to create the desired Constitutive Knockout (KO), Conditional Knockout (cKO), Knockin (KI) and Transgenic (Tg) vectors in the most efficient manner possible.


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Mouse Biology Shared Resource

The goal of Mouse Biology Shared Resource is to meet the needs of UC Davis Comprehensive Cancer Center investigators, utilizing genetically-altered mice for basic, clinical and translational research.


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Mouse Models

The generation of genetically modified mice may be divided into two main categories: targeted integration (insertion or deletion) and random integration of DNA into the mouse genome.


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Phenotyping

The MBP provides investigators with a full range of morphological, metabolic, organismal, behavioral, and pathological assays that can be fully customized to characterize mutant mouse models as adults and embryos.


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Rederivation

Strain rederivation is a management tool used to clean a mouse line from pathogen infection or to import mice into a barrier facility from an outside vivarium.


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Resuscitation

The MBP has over 20 years of experience collecting and cryopreserving mouse germplasm, which includes an established program for cryorecovering mouse strains.