Custom Model Generation Solutions
With the Mouse Biology Program, we are here to answer questions and develop a pathway for your research with custom mouse models.
Welcome to our Custom Model Generation Solutions, your gateway to creating tailored mouse models to meet your research needs. Whether you’re exploring gene function, modeling human diseases, or testing therapies, we support every step of your journey.
Why Choose Custom Models?
Custom mouse models allow researchers to:
- Study gene function with precision.
- Mimic human diseases for preclinical testing.
- Validate therapeutic targets in a controlled environment.
- Investigate genetic and molecular pathways in detail.
CRISPR-Cas9 Gene Editing
Achieve precise genetic modifications, including:
- Knockout Models: Remove a gene entirely to study its function.
- Knock-in Models: Add or modify genes to explore specific mutations.
- Point Mutations: Introduce or correct single nucleotide changes.
Transgenic Models
Generate models with integrated transgenes, such as:
- Reporter genes for visualizing gene expression.
- Overexpression or suppression constructs for functional studies.
Conditional Alleles
Control gene expression with:
- Tissue-specific modifications using Cre-Lox systems.
- Inducible models activated by external triggers.
Humanized Models
Introduce human genes, proteins, or cells for translational research in:
- Oncology
- Immunology
- Infectious diseases
How We Work With You
- Initial Consultation: Discuss your research goals with our experts.
- Model Design: Collaborate on the ideal genetic modifications for your study.
- Timeline and Costs: Receive a clear plan, including expected delivery and budget.
- Generation: From construct design to model validation, we handle it all.
- Validation and QC: Ensure your model is as specified through rigorous quality control.
- Delivery: Receive your live model, cryopreserved embryos, or ES cells.
Additional Support
- Phenotyping Services: Comprehensive testing to confirm the functional impact of genetic modifications.
- Colony Management: Breeding and maintaining your custom model to your specifications.
- Cryopreservation: Secure long-term storage of your model for future use.
Why Partner With Us?
- Expertise: Years of experience creating complex and precise mouse models.
- Collaboration: Tailored support and transparent communication throughout the process.
- Reliability: Stringent quality control ensures reproducible and accurate models.
Get Started Today!
Ready to create a custom mouse model? Contact our team to discuss your project and unlock the potential of tailored research solutions. Let us help you bring your scientific vision to life.
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