Oncology & Immuno-Oncology

Advancing cancer research with cutting-edge mouse models, comprehensive data, and expert support from experts at the Mouse Biology Program.

Our oncology and immuno-oncology services empower groundbreaking research in tumor biology, therapeutic development, and immune system interactions. By offering genetically engineered mouse models (GEMMs), humanized systems, comprehensive phenotyping, and immune response assays, we provide the tools and expertise needed for impactful cancer research. These resources enable researchers to investigate tumor growth, metastasis, and therapeutic response; assess the efficacy of immune checkpoint inhibitors, CAR-T cells, and combination therapies; and explore tumor-immune system interactions in a controlled and reproducible environment.

Mouse Models for Oncology Research
In Vivo Cancer Research Tools
Immune Profiling and Functional Assays
Data and Training Resources

Mouse Models for Oncology Research

We offer a diverse range of mouse models to support both basic and translational cancer research, including:

Genetically Engineered Mouse Models (GEMMs): For studying specific gene mutations in cancer development.
Syngeneic Tumor Models: Immunocompetent mouse strains with established tumor cell lines (e.g., MC38, B16-F10, 4T1) for immune response testing.
Humanized Mouse Models: Incorporating human immune cells to evaluate immunotherapeutics in a human-like immune context.

In Vivo Cancer Research Tools

We provide access to specialized tools and platforms to support preclinical oncology studies, such as:

In Vivo Imaging: Noninvasive systems for tracking tumor progression and immune cell trafficking in live animals.
Cryopreserved Tumor Models: Ready-to-use tumor lines for rapid study initiation.
Custom Tumor Implantation: Tailored services for orthotopic and subcutaneous tumor implantation.

Immune Profiling and Functional Assays

Our capabilities include detailed immune system analysis using state-of-the-art techniques:

Flow Cytometry: For immune cell phenotyping and tumor-infiltrating lymphocytes (TILs) analysis.
Cytotoxicity Assays: To evaluate the effectiveness of T-cell, NK-cell, and macrophage-mediated responses.
Multiplex Cytokine Assays: For assessing the tumor microenvironment and systemic immune responses.

Data and Training Resources

We provide access to critical datasets and training programs to support your research:

Phenotyping Data: Comprehensive information on tumor phenotypes and immune-related parameters.
Workshops and Training: Hands-on training in tumor implantation, immune monitoring, and experimental design.

Why Partner with Us?

Comprehensive Support: Our team is dedicated to supporting your research goals, from model selection to data analysis.
High-Quality Resources: Proven mouse models and validated assays for reproducible results.
Innovative Tools: Access to the latest platforms for preclinical oncology and immuno-oncology studies.

Get Started

Accelerate your oncology and immuno-oncology research with our robust resources and expert services today:

Email Us For Support in Your Oncology or Immuno-Oncology Efforts

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