Standard Pathology
Our Standard Pathology services offer a comprehensive approach to necropsy and tissue evaluation. Each complete necropsy includes a detailed examination of organs, weight measurement, and precise tissue collection to ensure accurate results for your study.
We provide a range of fixation, perfusion, and tissue preservation methods tailored to meet the specific needs of your research. These methods include traditional formalin fixation, rapid freezing, and specialized perfusion techniques to preserve delicate structures.
Whether you are investigating disease pathology, developmental biology, or toxicology, our team ensures that tissues are processed to the highest standards, allowing you to gain valuable insights from every specimen.
Blood Collection
Our Blood Collection services provide researchers with reliable options for repeated and terminal blood sampling. We offer serum, plasma, or whole blood collection tailored for hematology and clinical chemistry analysis, supporting various study needs.
For repeated sampling, we utilize minimally invasive techniques to reduce stress on the animal and ensure consistent results across time points. Terminal collection methods are designed to maximize yield, allowing for extensive analysis of biomarkers and other components.
Our facilities are equipped with state-of-the-art centrifugation and storage equipment, ensuring that blood samples are processed and preserved under optimal conditions for subsequent analysis.
Histopathology
Our Histopathology services provide a complete range of tissue processing options, including formalin-fixed paraffin-embedded (FFPE) and OCT-embedded frozen tissues. This enables precise structural preservation for a variety of downstream analyses.
Certified histotechnologists oversee each step of the process, from tissue fixation and embedding to slide production and staining. Our staining options include hematoxylin and eosin (H&E), immunohistochemistry (IHC), and specialized stains tailored to your research needs.
In addition, we offer consultation with a board-certified veterinary pathologist who specializes in mutant mouse pathology, providing expert interpretation of findings to guide your study conclusions and support publication-quality results.
Gene Expression Analysis
Our Gene Expression Analysis services offer a suite of tools to characterize gene and protein expression. Techniques include quantitative PCR (QPCR) for precise quantification of gene expression, β-galactosidase staining for lacZ reporter genes, and immunohistochemistry (IHC) for protein localization.
These methods are valuable for studying gene function, investigating protein interactions, and analyzing expression patterns in various tissues. Our team ensures that samples are processed with care, providing accurate and reproducible results.
We offer additional consultation services to design experiments and select the best methods for analyzing your target genes, supporting comprehensive analysis of genetic and protein-level changes in your study model.
Digital Imaging
Our Digital Imaging services provide advanced whole-slide scanning and digital image acquisition using the Aperio L2 platform. This technology captures high-resolution images of histological samples, allowing for detailed visualization and analysis.
Digital imaging is ideal for archiving, sharing, and analyzing data without compromising sample integrity. We offer annotation tools and software integration options that allow for seamless data sharing across research teams.
Whether you need detailed measurements, image analysis, or simply high-quality visuals for publication, our digital imaging capabilities support enhanced visualization and interpretation of your histological data.
