Gnotobiotic Mouse Resource Center (GMRC)

Advance your research with specialized projects using germ-free or gnotobiotic mouse models. These controlled systems—ranging from defined microbial communities to fully axenic mice—reveal host–microbe interactions and open new possibilities across diverse scientific studies.

The Gnotobiotic Mouse Resource Center (GMRC) offers comprehensive services supporting microbiota studies, specializing in germ-free conditions and managing gnotobiotic experiments. Services include:

• Breeding and Colony Management: Setting up and maintaining breeding units with live data updates through the MOSAIC colony management database.
• Tailored Housing Options: Mice are housed in flexible isolators or individually ventilated cages, meeting specific research requirements while ensuring a controlled, sterile environment.
• Precise Genotyping and Identification: Ear notching and tail cutting are performed for genotyping, with tissue samples available for in-house testing or customer pickup.
• Sterility Assurance: Frequent microbiological testing confirms isolator sterility, maintaining a pathogen-free environment for reliable results.
• Specialized Procedures: Services include colonization of defined flora via gavage, body weight monitoring, and fecal and urine collection for detailed analysis.

By combining expertise in gnotobiotic studies with state-of-the-art facility protocols, the GMRC ensures accuracy and reproducibility, supporting your microbiome research from start to finish.

• Vivaria and Health Services
• Colony Management Services
• Breeding Management Consultation
• Custom Breeding and Colony Management
• Gnotobiotic Mouse Resource Center (GMRC)
• Quarantine Procedures
• Ultra Clean Housing Facility
• Veterinary Services