Behavioral Phenotyping

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Genetically altered mutant mice or diseased model mice may develop significant behavioral abnormalities due to their induced mutation or pathology. MBP has a full-service behavioral core facility dedicated to assisting research scientists in characterizing their mouse models for developmental delay, reduced executive and motor functions, and complex neurological disorders such as anxiety, autism, and schizophrenia.

Standardized behavioral tests are available for “high-throughput” screening of mutants to quickly and efficiently detect abnormalities in memory, motivation, learning, cognitive, motor, and sensorimotor functions. These tests provide reliable and reproducible results, allowing researchers to assess various behavioral and neurological phenotypes. MBP’s behavioral core employs advanced techniques like open field testing, elevated plus maze, rotarod, and Morris water maze, among others, to evaluate mice’s anxiety, motor coordination, spatial learning, and memory.

Furthermore, customizable behavioral assays are available to address specific research questions, enabling tailored approaches to study complex behavioral phenotypes. These services are designed to support researchers in gaining a deeper understanding of the impact of genetic modifications or diseases on behavior and cognition, thereby advancing studies in neurodevelopmental disorders, psychiatric diseases, and neurodegenerative conditions.

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Computational, interpretative, and consulting services are all available upon request.

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• Phenotyping Services
• Behavioral Phenotyping
• Embryo Phenotyping
• Experimental Design Services
• Embryonic Stem (ES) Cell Targeting
• Live Mouse Imaging Services
• Metabolic Phenotyping
• Morphological and Physiological Phenotyping
• Sperm Phenotyping