Mouse Pathobiology Courses

TIER 1: Foundations of Mouse Pathobiology

Student qualifications: Suitable for graduate and undergraduate students, research assistants and associates, senior researchers, post-doctoral fellows, and all technical laboratory personnel.

Course organization and content:  Mouse Husbandry and Biology (Mouse Pathology Part A): Gain foundational knowledge in the handling and use of the research mouse, along with normal mouse biology and general pathology. Topics include the history of the laboratory mouse, mouse husbandry, regulations and laboratory accreditation, normal gross anatomy, normal mouse histology, and general pathology. Mouse Pathobiology (Mouse Pathology Part B): Gain a comprehensive introduction to the pathobiology of the genetically-engineered mouse, emphasizing the correlation of microscopic findings to clinical and gross observations. Topics include gross and microscopic patterns of disease, basics of necropsy, gene insertion and removal, primary pathology, immunology, and reproductive physiology, and toxicological pathology. Also covers experimental design and the responsible use of mouse models in research.

TIER 2: Mouse Models for Cancer Research 

Student qualifications: Suitable for principal investigators, senior academic and professional researchers,  and advanced technical laboratories.

Course organization and content: The Mouse as a Model for Mammary Gland Cancer (BIOSCI 580): This course provides background information necessary to function in mammary tumor biology. It includes case examples and interactive conferences and is designed for the trained scientist (Ph.D., M.D., D.V.M.) with exposure to but limited training in comparative pathology and the use of genetically engineered mice to model human mammary disease.